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1.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2015; 25 (6): 395-398
in English | IMEMR | ID: emr-165636

ABSTRACT

To establish whether the Ischemia-Modified Albumin [IMA], a new parameter of oxidative stress, has diagnostic role in experimental acute pancreatitis. Randomized controlled trial. Experimental Animal Center, Canakkale Onsekiz Mart University, Canakkale, Turkey, from May to September 2013. Sixteen Sprague-Dawley rats were randomly divided into two groups [n=8 each]: Sham and AP groups. AP was induced by ligation of pancreatic duct. Serum IMA, amylase, lipase, AST, ALT and CRP were determined. The severity of pancreatitis was scored by a blinded pathologist under microscope. Serum IMA levels in the AP group increased significantly compared with the control group [p < 0.05]. There was also a strong positive correlation between amylase and IMA levels. The present study showed in a rodent model that serum IMA might serve as an additional marker to monitor inflammation during pancreatitis

2.
Anaesthesia, Pain and Intensive Care. 2014; 18 (3): 291-293
in English | IMEMR | ID: emr-164537

ABSTRACT

Obesity leads to several changes in both airway and drug metabolism. The problems are compounded in cases of super super morbid obesity. Gastric banding surgery for weight loss was planned for a 47 year old, super-super morbidly obese female patient [164 kg and 151 cm, BMI: 72 kg/m[2] On pre-operative examination, patient had a short thick neck and grade 4 Mallampatti class. Induction of anesthesia was done in the sitting / semi-sitting position Maintenance was provided with 6% desflurane and O[2]/air mixture. Remifentanil infusion of 0.05 [xg/kg was administered during surgery. Patient had an uneventful recovery. The use of short acting drugs and appropriate monitoring provided hemodynamic stability and a fast and smooth recovery

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